Effect of strychnine hydrochloride on liver cytochrome P450 mRNA expression and monooxygenase activities in rat
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چکیده
منابع مشابه
Effect of regular organic solvents on cytochrome P450-mediated metabolic activities in rat liver microsomes.
The effects of regular organic solvents on the metabolic activities of various human cytochromes P450 (P450s) have been reported. However, very little is known about their influence on metabolic activities mediated by P450s in the rat liver microsomes (RLM). The purpose of this study was to investigate the effects of organic solvents such as methanol, acetonitrile, dimethyl sulfoxide (DMSO), ac...
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CONTEXT Kanglaite (KLT) is an oily substance extracted from Coix lacryma-jobi Linn. (Cramineae) and has been proved to significantly improve the life span and quality of life of patients, when combined with chemotherapy, radiotherapy, or surgery. OBJECTIVE The purpose of this study was to find out whether KLT influences the effect on rat cytochrome P450 (CYP) enzymes (CYP1A2, CYP2B6, CYP2C9, ...
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The results of a limited number of studies on echinoderms provide evidence for the presence of a cytochrome P450 monooxygenase system in representatives of three classes of the phylum Echinodermata: the asteroids (sea stars), holothuroids (sea cucumbers) and echinoids (sea urchins). The monooxygenase system has been demonstrated to be involved in the metabolism of xenobiotic compounds, but is a...
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ژورنال
عنوان ژورنال: Acta Pharmaceutica Sinica B
سال: 2011
ISSN: 2211-3835
DOI: 10.1016/j.apsb.2011.06.009